Covid-19: can we be immunized without having contracted the disease?

Research into a vaccine or treatment to fight Covid-19, which has been raging for several months in the world continues … If immunity sometimes seems to be confirmed in people who have been affected by the virus, asymptomatically or under a more severe form of the disease, doctors are looking to identify other ways to immunize the population.

Several studies also agree that immunity could be possible without having contracted the disease.

Immunity: an antibody generated during previous infections?

Work, carried out by Andreas Thiel and his team of researchers from the University of Berlin (Germany), and published in the scientific journal Nature, revealed the presence of CD4 T lymphocytes, both in patients with Covid-19 (in 83% of cases), and in test participants who were not exposed to the virus (in 35% of case).

What interests specialists is that these lymphocytes are cells that secrete antibodies, and they could play an important role in immunity.

“Probably generated during past encounters with endemic coronaviruses”, these antibodies could therefore be present in the body of some people, who have never contracted the disease.

As German specialists specify, further research is needed to confirm this hypothesis, but could be useful in the search for a vaccine against Covid-19.

The use of synthetic antibodies before the discovery of a vaccine?

Same hypothesis on the side of American researchers, whose study was published in the journal Science. They believe that “Synthetic antibodies could fight COVID-19 before vaccines arrive”, and that research in this area should be faster than developing a vaccine, which is based on antigenic agents that will trigger the immune response.

These synthetic antibodies could be a “cocktail Covid-19”, formulated on the basis of a monoclonal antibody (i.e. derived from a single cell line) capable, in the event of contact with the virus, of “neutralize” infection before it occurs.

According to them, “these antibodies could protect healthcare workers most at risk from infection while reducing the severity of COVID-19 illness in hospitalized patients.

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